Lomax, Elizabeth (1973). "The Uses and Abuses Of Opiates In Nineteenth-Century England". Bulletin of the History of Medicine. 47 (2): 167–176. ISSN 0007-5140. JSTOR 44447528. PMID 4584236 . Retrieved May 31, 2022. Opium production in the Golden Triangle continues at high levels, threatening regional integration". unodc.org . Retrieved April 4, 2016. Protocol for Limiting and Regulating the Cultivation of the Poppy Plant, the Production of, International and Wholesale Trade in, and Use of Opium

Use of opium as a cure-all was reflected in the formulation of mithridatium described in the 1728 Chambers Cyclopedia, which included true opium in the mixture.Heroin is classified as a Schedule I drug under the Controlled Substances Act of 1970 and as such has no acceptable medical use in the United States. a b Rewriting history, A response to the 2008 World Drug Report, Transnational Institute, June 2008 Forbes, Andrew; Henley, David (2011). Traders of the Golden Triangle. Chiang Mai: Cognoscenti Books. ASIN B006GMID5K

The earliest clear description of the use of opium as a recreational drug in China came from Xu Boling, who wrote in 1483 that opium was "mainly used to aid masculinity, strengthen sperm and regain vigor", and that it "enhances the art of alchemists, sex and court ladies". He also described an expedition sent by the Ming dynasty Chenghua Emperor in 1483 to procure opium for a price "equal to that of gold" in Hainan, Fujian, Zhejiang, Sichuan and Shaanxi, where it is close to the western lands of Xiyu. A century later, Li Shizhen listed standard medical uses of opium in his renowned Compendium of Materia Medica (1578), but also wrote that "lay people use it for the art of sex," in particular the ability to "arrest seminal emission". This association of opium with sex continued in China until the end of the 19th century. Alfred W. McCoy (1972). "The politics of heroin in Southeast Asia". Archived from the original on October 7, 2007 . Retrieved September 24, 2007. Great Britain, India office (1922). The truth about Indian opium. [London] Printed by H.M. Stationery Off.Hayatbakhsh M, Oghabian Z, Conlon E, Nakhaee S, Amirabadizadeh A, Zahedi M, et al. Lead poisoning among opium users in Iran: an emerging health hazard. Substance Abuse Treatment, Prevention, and Policy. 2017;12(43). Beginning in 1915, Chinese nationalist groups came to describe the period of military losses and Unequal Treaties as the "Century of National Humiliation", later defined to end with the conclusion of the Chinese Civil War in 1949. [78] Robinson SL, Rowbotham DJ, Smith G (July 1991). "Morphine compared with diamorphine. A comparison of dose requirements and side-effects after hip surgery". Anaesthesia. 46 (7): 538–40. doi: 10.1111/j.1365-2044.1991.tb09650.x. PMID 1862890. S2CID 35289009.

Morewood, Samuel (1838). A philosophical and statistical history of the inventions and customs of ancient and modern nations in the manufacture and use of inebriating liquors; with the present practice of distillation in all its varieties: together with an extensive illustration of the consumption and effects of opium, and other stimulants used in the East, as substitutes for wine and spirits. Dublin, W. Curry and W. Carson. a b Commissioner Jesse B. Cook (June 1931). "San Francisco's Old Chinatown". San Francisco Police and Peace Officers' Journal . Retrieved September 22, 2007. Brzezinski, Matthew. "Re-Engineering the Drug Business". The New York Times Magazine, June 23, 2002

Pharmacy product

The opium trade under the Chinese Communist Party was important to its finances in the 1940s. [82] Peter Vladimirov's diary provided a first hand account. [83] Chen Yung-fa provided a detailed historical account of how the opium trade was essential to the economy of Yan'an during this period. [84] Mitsubishi and Mitsui were involved in the opium trade during the Japanese occupation of China. [85] Thelwall, A. S. (1839). The iniquities of the opium trade with China; being a development of the main causes which exclude the merchants of Great Britain from the advantages of an unrestricted commercial intercourse with that vast empire. With extracts from authentic documents. London: Wm. H. Allen and Co. Hardening of Canadian attitudes toward Chinese opium users and fear of a spread of the drug into the white population led to the effective criminalization of opium for nonmedical use in Canada between 1908 and the mid-1920s. [92]

Ballantyne, Jane C., and Jianren Mao. "Opioid Therapy For Chronic Pain". New England Journal of Medicine 349.20 (n.d.): 1943–1953. SocINDEX with Full Text. Web. November 3, 2011.Letter from Macfarlan Smith". Archived from the original on March 22, 2009 . Retrieved March 21, 2010. Opium smoking began as a privilege of the elite and remained a great luxury into the early 19th century. However, by 1861, Wang Tao wrote that opium was used even by rich peasants, and even a small village without a rice store would have a shop where opium was sold. [47] Afghan opium poppy cultivation plunges by 95 percent under Taliban: UN". Al Jazeera . Retrieved November 7, 2023. Trafkowski, J; Madea, B; Musshoff, F (August 2006). "The significance of putative urinary markers of illicit heroin use after consumption of poppy seed products". Therapeutic Drug Monitoring. 28 (4): 552–8. doi: 10.1097/00007691-200608000-00011. PMID 16885724. S2CID 22585610.