Vitamin E Capsules 400IU - 180 High Strength Softgels - 6 Month Supply - Natural D-Alpha Tocopherol - High Absorption - Hair, Skin & Nails Supplement

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Vitamin E is a group of eight fat soluble compounds that include four tocopherols and four tocotrienols. [1] [2] Vitamin E deficiency, which is rare and usually due to an underlying problem with digesting dietary fat rather than from a diet low in vitamin E, [3] can cause nerve problems. [4] Vitamin E is a fat-soluble antioxidant which may help protect cell membranes from reactive oxygen species. [2] [4] Worldwide, government organizations recommend adults consume in the range of 3 to 15mg per day. As of 2016, consumption was below recommendations according to a worldwide summary of more than one hundred studies that reported a median dietary intake of 6.2mg per day for alpha-tocopherol. [5] Heart health: Some research suggests that the antioxidant effects of vitamin E could help protect against some risk factors for heart disease. However, other studies have turned up conflicting findings on the effects of supplementation ( 5). Chiu A, Kimball AB. Topical vitamins, minerals and botanical ingredients as modulators of environmental and chronological skin damage. Br J Dermatol. 2003 Oct;149(4):681-91. doi: 10.1046/j.1365-2133.2003.05540.x

Guidelines on food fortification with micronutrients". World Health Organization. 2006 . Retrieved 12 December 2022. a b Christopher Min K (2007). "Structure and Function of α‐Tocopherol Transfer Protein: Implications for Vitamin e Metabolism and AVED". Structure and function of alpha-tocopherol transfer protein: implications for vitamin E metabolism and AVED. Vitamins & Hormones. Vol.76. pp.23–43. doi: 10.1016/S0083-6729(07)76002-8. ISBN 978-0-12-373592-8. PMID 17628170.Distribution of vitamin E to tissues, via the lymphatic system, occurs as a lipoprotein complex. High concentrations of vitamin E are found in the adrenals, pituitary, testes and thrombocytes. Chylomicron remnants, containing newly absorbed vitamin E, are taken up by the liver. Vitamin E is secreted from the liver in very low density lipoproteins. Plasma vitamin E concentrations depend upon the secretion of vitamin E from the liver.

measuring the plasma α-tocopherol level (level < 5μg/mL or <11.6 μmol/L indicates vitamin E deficiency) and/or Georgousopoulou EN, Panagiotakos DB, Mellor DD, Naumovski N (January 2017). "Tocotrienols, health and ageing: A systematic review" (PDF). Maturitas. 95: 55–60. doi: 10.1016/j.maturitas.2016.11.003. PMID 27889054. Vitamin E is a fat-soluble vitamin, meaning it is stored in your body for when you need it. It is present in foods such as avocados, nuts, seeds, vegetable oils and some green veg. The World Health Organization does not have any recommendations for food fortification with vitamin E. [54] The Food Fortification Initiative does not list any countries that have mandatory or voluntary programs for vitamin E. [55] Infant formulas have alpha-tocopherol as an ingredient. In some countries, certain brands of ready-to-eat cereals, liquid nutrition products and other foods have alpha-tocopherol as an added ingredient. [53] Non-nutrient food additives [ edit ]

Vitamin E Deficiency

Serum concentration increases with age. This is attributed to the fact that vitamin E circulates in blood incorporated into lipoproteins, and serum lipoprotein concentrations increase with age. Infants and young children have a higher risk of being below the deficiency threshold. [5] Cystic fibrosis and other fat malabsorption conditions can result in low serum vitamin E. Dietary supplements will raise serum vitamin E. [3] Research [ edit ] Arain MA, Abdul Qadeer A (April 2010). "Systematic review on "vitamin E and prevention of colorectal cancer" ". Pakistan Journal of Pharmaceutical Sciences. 23 (2): 125–30. PMID 20363687. Vitamin E oral. Facts & Comparisons eAnswers. http://www.wolterskluwercdi.com/facts-comparisons-online/. Accessed Aug. 10, 2017. Worldwide, consumption is below recommendations according to a summary of more than one hundred studies that reported a median dietary intake of 6.2mg per day for alpha-tocopherol. [5] Of the many different forms of vitamin E, gamma-tocopherol ( γ-tocopherol) is the most common form found in the North American diet, but alpha-tocopherol ( α-tocopherol) is the most biologically active. [2] [52] Palm oil is a source of tocotrienols. [20]