However, calming vets or collars may last anywhere from a few hours to a few days. Likewise, supplements with natural ingredients such as L-theanine or melatonin may last up to 8 hours or more. In cases of extreme stress and agitation we recommend you consult with your vet first. What differences can I expect from a dog calming supplement like PRO PLAN ® Relax +?* Siracusa C, Manteca X, Cuenca R, et al. (2010) Effect of a synthetic appeasing pheromone on behavioral, neuroendocrine, immune, and acute-phase perioperative stress responses in dogs. Journal of the American Veterinary Medical Association. 2010;237:673–681. New situations – do new environments or new people cause a strong reaction in your dog, or do they struggle to cope? Palestrini C, Minero M, Cannas S, et al. Efficacy of a diet containing caseinate hydrolysate on signs of stress in dogs. Journal of Veterinary Behavior. 2010;5(6):309-317.

MULTI-BILLION PROBIOTIC: This canine, feline, and pet friendly high count formula improves the microbial balance within the intestines and removes harmful pathogenic bacteria from the digestive system. Simply add a scoop to cat, dog or any pet food SUITABLE FOR ALL PETS, SIZES & BREEDS: Whether you have a cat, dog, kitten, puppy, senior, horse, ferret, or rabbit, our oil is suitable for ALL pets. Just adjust the serving size in line with the small to extra-large sized pet chart on the bottle. Drowsiness. Though chamomile, valerian root, and L-tryptophan are considered safe and effective at quelling anxiety, these ingredients made our dogs a little sleepy. Melatonin. Melatonin can also increase the functioning of GABA in the brain and reduce the feeling of fear. Melatonin is generally considered safe by vets, but there aren’t many canine-specific studies. As always, consult your vet before giving your dog melatonin-based supplements. Watch out for ones with xylitol as an ingredient.L-tryptophan has been added to some veterinary calming diets. One research study showed that one of these diets (which also contains alpha-casozepine) helped dogs to better cope with stress, while another study showed no effect on the dogs’ anxiety levels. Valerian Andersen L, Werner M, Rosenberg J, et al. A systematic review of peri-operative melatonin. Anaesthesia. 2014;69(10):1163–1171. PRO PLAN ® Relax + is an everyday dog calming supplement to help your dog handle life's challenges. DOGS, CATS & PETS LOVE IT: Hiding capsules and medication in your pets food can be very frustrating. Instead, simply pump the delicious liquid gel treat over your pets meal or medication and watch them devour every last drop. No mess, no fuss. Yum!

Alpha-casozepine is a lactose-free derivative of a protein in cows’ milk. Some research studies have suggested that this derivative helps reduce anxiety in dogs by acting on gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the brain that produces a calming effect. Gaultier E, Bonnafous L, Vienet-Legue D, et al. Efficacy of dog appeasing pheromone in reducing behaviours associated with fear of unfamiliar people and new surroundings in newly adopted puppies. Veterinary Record. 2009;164:708–714. Cottam N, Dodman N, Ha J. The effectiveness of the Anxiety Wrap in the treatment of canine thunderstorm phobia: An open label trial. Journal of Veterinary Behavior. 2013;8:154–161. Adaptil (Ceva) spray can be applied to a crate or kennel or sprayed in a vehicle. The spray contains an alcohol base with an odor that dogs may not like, so spray it and wait at least 15 minutes before exposing your dog to that space, so the odor can dissipate. The effects last about 4-5 hours.Dog diets supplemented with omega 3 fatty acids appear to promote calmer behaviours in response to stressors, although the full mechanism of action is not fully understood. Sheppard G, Mills D. Evaluation of dog-appeasing pheromone as a potential treatment for dogs fearful of fireworks. Veterinary Record. 2003;152:432–436. Frank D, Beauchamp G, Palestrini C. Systematic review of the use of pheromones for treatment of undesirable behavior in cats and dogs. Journal of the American Veterinary Medical Association. 2010:236(12):1308­­­-1316. Pankratz K, Korman J, Emke C, et al. Randomized, placebo-controlled prospective clinical trial evaluating the efficacy of the Assisi anti-anxiety device (Calmer Canine) for the treatment of canine separation anxiety. Frontiers in Veterinary Science. 2021;20(8):775092.

Dewey C, Davies E, Xie H, et al. Canine cognitive dysfunction: pathophysiology, diagnosis, and treatment. Veterinary Clinics of North America: Small Animal Practice. 2019;49(3):477–499. This is why it is important to discuss with your veterinarian starting any supplement, even if you can buy it over the counter, before giving it to your pet. Common Ingredients in Behavioral Supplements for Dog Anxiety Palatability. Our dogs LOVED these chews! This supplement is one of the most palatable options on our list.When it comes to supplements and aromatherapy calming products for dogs, you want to be sure that they contain effective ingredients that can actually soothe your dog’s anxiety. Here are some ingredients to look for: Calming products for dogs are available in several different types, which often correspond to the type of anxiety that your dog suffers from.

Valerian is a plant that may help pets sleep through the night and may ease anxiety. However, controlled research studies are not available. Mills D, Estelles M, Coleshaw P, et al. Retrospective analysis of the treatment of firework fears in dogs. Veterinary Record. 2003;153:561–562. Owners who are looking for a sedative to give to their dogs at home are somewhat limited in their choices. Kato M, Miya K, Ohtani N, et al. Effects of prescription diet on dealing with stressful situations and performance of anxiety-related behaviors in privately owned anxious dogs. Journal of Veterinary Behavior. 2012;7(1):21-26.

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L-tryptophan is another amino acid that can help boost your dog’s mood and supports his stress response.